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Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51
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コメント "ヒトDNAプリマースの [4Fe4S] クラスタは,DNA電荷輸送を用いた酸化還元スイッチとして機能する"

Luca Pellegrini1

  • 1Department of Biochemistry, University of Cambridge, Cambridge, UK.

Science (New York, N.Y.)
|July 22, 2017
PubMed
まとめ

プライマース酵素における鉄硫黄のクラスターは,それらの活動において酸化還元作用を起します. 正しく折りたたまれた構造は,チロシンがRNA/DNAヘリックスに接触することを示唆し,酵素の機能に関する新しい説明を提供します.

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