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In-vivo Detection of Protein-protein Interactions on Micro-patterned Surfaces
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In-vivo Detection of Protein-protein Interactions on Micro-patterned Surfaces

Published on: March 19, 2010

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プロテイン・プロテイン・インターフェースの空いた表面をターゲットにする

David Rooklin1, Ashley E Modell1, Haotian Li1

  • 1Department of Chemistry, New York University , New York, New York 10003, United States.

Journal of the American Chemical Society
|August 1, 2017
PubMed
まとめ

タンパク質とタンパク質の相互作用を 標的としたペプチドミメティック阻害剤を作るために アルファスペースを使って 計算設計戦略を開発しました この方法は,KIX/MLL標的の抑制剤を成功裏に設計し,薬剤発見の可能性を示しました.

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