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Updated: Feb 25, 2026

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae
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マルチ侵入は,染色体再配置を誘発する再結合副産物である

Aurèle Piazza1, William Douglass Wright1, Wolf-Dietrich Heyer2

  • 1Department of Microbiology and Molecular Genetics, One Shields Avenue, University of California, Davis, Davis, CA 95616, USA.

Cell
|August 8, 2017
PubMed
まとめ

マルチ侵入誘発再配置 (MIR) と呼ばれる新しいDNA修復経路は染色体の転位を引き起こす可能性があります. 壊れたDNA末端が 完ぺきな染色体に侵入することで引き起こされる この過程は DNAのさらなる損傷につながり 病気にも影響を及ぼします

キーワード:
Dループクロモトリプシスエンドヌクレアゼゲノムの不安定性ヘリコース同型再結合ホモロジー検索マルチインヴァージョントランスロケーション

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