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Updated: Feb 25, 2026

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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ブラフキナーゼ不活性変異体が肺腺癌を誘発する

Patricia Nieto1, Chiara Ambrogio1, Laura Esteban-Burgos1

  • 1Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain.

Nature
|August 8, 2017
PubMed
まとめ

BRAF変異の不活性化により,MAPKのシグナル伝達が変化し,肺腺がんが発症する. ワイルド型BRAFは腫瘍の成長に不可欠で その喪失は致命的な病変につながる可能性があります

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