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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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アルケンの銅触媒による非対称な水酸化に関するメカニズム研究

Yumeng Xi1, John F Hartwig1

  • 1Division of Chemical Sciences, Lawrence Berkeley National Laboratory, and Department of Chemistry, University of California , Berkeley, California 94720, United States.

Journal of the American Chemical Society
|August 9, 2017
PubMed
まとめ

この研究は,銅で触媒化された非対称な水溶解における重要な触媒中間物質を明らかにした. DTBM-SEGPHOSリガンドは,フェネチル銅の中間体を通して効率的なビニラレン水酸化を可能にするが,SEGPHOSは不活性な銅水化物につながる.

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