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Updated: Feb 25, 2026

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling
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誘導可能なdCas9システムによる化学的に制御されたエピゲノム編集

Tingjun Chen1, Dan Gao1, Roushu Zhang1

  • 1Department of Chemistry and Chemical Biology, University of New Mexico , 300 Terrace Street NE, Albuquerque, New Mexico 87131, United States.

Journal of the American Chemical Society
|August 9, 2017
PubMed
まとめ

特定の遺伝子の位置で ヒストンのアセチル化を 正確に制御する 新しい誘導システムを開発しました このツールは,ヒストンの改変と遺伝子活性化タイミングと安定性の間の直接的なリンクを理解するのに役立ちます.

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