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Updated: Feb 24, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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テトラ置換オレフィンの非対称性水素化における最近の進歩

Stefan Kraft1, Kristen Ryan1, Robert B Kargbo1

  • 1Drug Discovery Services, Medicinal Chemistry, Albany Molecular Research Inc. , 26 Corporate Circle, Albany, New York 12201-5098, United States.

Journal of the American Chemical Society
|August 12, 2017
PubMed
まとめ

テトラ置換オレフィンの非対称な水素化は,生物学的分子を合成するために困難ですが,不可欠です. 最近のキラル触媒の進歩は,これらの反応における効率的な非対称誘導のための新しい機会を提供します.

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Metals like palladium, platinum, and nickel are commonly used in their solid forms — fine powder on an inert surface. As these catalysts remain insoluble in the reaction mixture, they are referred to as heterogeneous catalysts.
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