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Updated: Feb 24, 2026

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
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抗CTLA-4と抗PD-1チェックポイントブロックの基礎となる明確なセルラーメカニズム

Spencer C Wei1, Jacob H Levine2, Alexandria P Cogdill3

  • 1Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Cell
|August 15, 2017
PubMed
まとめ

抗CTLA-4および抗PD-1療法を含む免疫チェックポイントブロックは,腫瘍における特定のT細胞サブセットを標的とする. これらの治療法は 免疫細胞の特定のメカニズムを活性化し 異なる経路で腫瘍の拒絶につながります

キーワード:
CTLA-4 についてPD-1 についてT細胞チェックポイントの封鎖コスティミュレーションホストの免疫反応マスサイトメトリーメラノーマ腫瘍腫瘍に浸透するリンパ球

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