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Updated: Feb 23, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
10:13

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

Published on: June 9, 2017

17.3K

コメンサル細菌は,ヒトのシグナル伝達分子を模倣するGPCRリガンドを作ります

Louis J Cohen1,2, Daria Esterhazy3, Seong-Hwan Kim1

  • 1Laboratory of Genetically Encoded Small Molecules, Rockefeller University, New York, New York 10065, USA.

Nature
|August 31, 2017
PubMed
まとめ

コメンサル細菌は,宿主Gタンパク質結合受容体 (GPCRs) と相互作用し,代謝ホルモンとグルコースホメオスタシスに影響を与えるN-アシルアミドを生成する. これは潜在的な治療方法として 微生物の生物合成遺伝子治療を示唆しています

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Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells14:02

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

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