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Updated: Feb 23, 2026

A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9
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A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9

Published on: August 28, 2018

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PCSK9阻害剤のエヴォロキュマブで非常に低いLDLコレステロール濃度を達成する臨床効果と安全性: FOURIER試験の予め指定された二次分析

Robert P Giugliano1, Terje R Pedersen2, Jeong-Gun Park1

  • 1TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Lancet (London, England)
|September 2, 2017
PubMed
まとめ

エヴォロキュマブで非常に低いLDLコレステロールレベルを達成すると,安全性の懸念なしに心血管疾患のリスクが著しく低下します. これらの発見は,LDLコレステロールを心血管疾患の患者に対する現在のガイドライン以下に低下させることを支持しています.

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