精神障害者のための病院の看護師のB型肝炎ワクチン接種に関する経験
E A Follett1, I S Symington, M G Cameron
1Regional Virus Laboratory, Ruchill Hospital, Glasgow.
Lancet (London, England)
|September 26, 1987
まとめ
病院スタッフのB型肝炎ワクチン接種は高い抗体反応を示したが,タイトルは時間の経過とともに減少した. ブースター投与は一部に効果があり,継続的な保護のためにリコールシステムを必要とした.
科学分野:
- 肝臓病理学 肝臓病理学
- 免疫学 免疫学とは
- 公衆衛生は公衆衛生である.
背景:
- B型肝炎ウイルス (HBV) 感染症は,医療機関,特に患者と直接接触するスタッフにとってリスクをもたらします.
- 精神障害者のための病院のスタッフは,HBVの暴露のリスクの高いグループとして特定されています.
研究 の 目的:
- 病院スタッフのHBV感染の程度を調査する.
- 医療従事者におけるB型肝炎ワクチン接種の有効性を評価する.
- 抗体応答,タイトルの減少,およびブースター用量の必要性を評価するために.
主な方法:
- B型肝炎ワクチン接種は,患者と直接接触している看護師に提供されました.
- ワクチン接種後9か月で500人の抗体位を測定した.
- ブースター用量に対する反応は,不応答者および位数が低下している人群で評価されました.
主要な成果:
- ワクチン接種を受けたスタッフの96%は,ワクチン接種後9ヶ月で検出可能な抗体を持っていた.
- 59.4%が高抗体位数 (>1000 IU/l) を達成した.
- 女性と若い個人は,ワクチンの反応が良くなった. 抗体タイトルは急速に低下したが,ブースター投与は,初期レベルが100IU/l以上の患者でタイトルを回復させた.
結論:
- B型肝炎ワクチン接種は,リスクの高い病院スタッフに抗体を誘発するのに非常に効果的です.
- 抗体レベルは時間とともに低下し,モニタリングとブースターワクチン接種の必要性を示している.
- リコールシステムは,長期的な免疫を管理し,医療従事者のHBV感染を予防するために不可欠です.
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