幼児期における無症状のバクテリウリアが,その後の妊娠に及ぼす影響
S H Sacks1, K Verrier Jones, R Roberts
1Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford.
Lancet (London, England)
|October 31, 1987
まとめ
幼児期における尿路感染症 (UTI) の病歴のある女性は,妊娠中に急性ピエロネフライトスおよびプレエクラムプシアの発生率の増加を含むより高いリスクに直面し,特に腎臓の痕がある場合は特にそうである. 幼児のアパガースコアもこれらの妊娠で低い.
科学分野:
- 産婦人科と産婦人科を担当しています.
- 感染症 感染症は感染症です.
- 小児科は小児科です.
背景:
- 幼児期の尿路感染症 (UTI) は,長期的な健康上の影響を及ぼす可能性があります.
- 再発性尿路感染症や腎臓の傷につながる感染症は,将来の妊娠の結果に影響を与える可能性があります.
- これらのリスクを理解することは,母と乳児の健康管理に極めて重要です.
研究 の 目的:
- 幼児期バクテリウリア歴のある女性の妊娠結果を,健康な対照群と比較するために.
- 妊娠合併症に対する以前の尿路感染症と腎臓の傷の影響を調査する.
- 母親の健康,出産方法,幼児の福祉への影響を評価する.
主な方法:
- 比較試験の設計が用いられました.
- 幼児期バクテリウリア歴のある34人の女性 (52人の妊娠) の妊娠結果を追跡し,正常な対照妊娠と比較した.
- 評価された主なアウトカムには,バクテリウリアの有病率,ピエロネフライト,プレエクラムプシア,出産介入,乳児のApgarスコアが含まれていました.
主要な成果:
- 以前は細菌性であった女性は,妊娠中に細菌性尿症 (35%対5%) と急性ピエロネフライト (10%対4%) の割合が著しく高かった.
- 前出血栓症は,以前バクテリア性であった女性で腎臓の痕 (p < 0.001) がより頻繁に発生しました.
- 腎臓の傷跡のある女性は,産科誘導 (44%) と手術による出産 (57%) を受ける可能性が高く,彼らの乳児はアパガースコアが低い.
結論:
- 幼児期バクテリウリア,特に腎臓の痕は,妊娠中にピエロネフライトと前出血栓症のリスクの増加と関連しています.
- 以前バクテリア性であった女性の腎臓の痕は,産科介入の割合が高く,乳児のApgarスコアが低いと相関しています.
- 胎児のアウトカムは満足のいくものであったが,小児性尿路感染症の歴のある妊婦の場合は,注意深いモニタリングが必要である.
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