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子どもの胃腸内科の進歩
Paul K H Tam1, Patrick H Y Chung1, Shawn D St Peter2
1Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Lancet (London, England)
|September 14, 2017
まとめ
最低侵襲手術は小児の胃腸外科手術において,特に一般的な疾患では有望である. 新生児の稀な疾患や 生存者の長期ケアについてはさらなる研究が必要である.
科学分野:
- 小児外科
- 胃腸 外科
- 新生児の手術
背景:
- 小児の胃腸外科では,最小侵襲手術 (MIS) が進んでいる.
- MISの恩恵は 盲腸炎のような一般的な疾患に よく確立されています
- 臨床試験のデータが限られているため,稀な新生児の胃腸疾患に対するMISの適用は困難です.
研究 の 目的:
- 小児胃腸外科における最近の発展を振り返る.
- 希少な新生児疾患の臨床的証拠の必要性を強調する.
- 遺伝学と幹細胞治療を含む 将来の研究方向について議論する
主な方法:
- 小児および新生児の胃腸外科手術に関する最新の文献のレビュー
- 最小侵襲的アプローチを支持する証拠の分析
- 珍しい病気に関する課題と将来の研究ニーズについて議論する.
主要な成果:
- 最低侵襲手術は 常見の小児胃腸疾患の有力な証拠で裏付けられています
- 希少な新生児疾患の臨床試験は困難ですが 極めて重要です
- 専門化と連携により 胆管不全などの治療結果が改善されました
結論:
- 小児と新生児の胃腸外科手術の進歩には 質の高い証拠が不可欠です
- 未来の研究は 希少疾患,長期的後遺症,および根本的な病原性に焦点を当てるべきである.
- 遺伝学と幹細胞治療は ヒルシュスプリング病のような疾患の 可能性を秘めています
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