関連する実験動画

Updated: Feb 22, 2026

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast
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ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast

Published on: June 30, 2022

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Saccharomyces cerevisiaeからのイントロン・ラリアット・スプリセソームの構造

Ruixue Wan1, Chuangye Yan1, Rui Bai1

  • 1Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China.

Cell
|September 19, 2017
PubMed
まとめ

この研究は,イントロン・ラリアット・スプリセソーム (ILS) 複合体の冷凍電子顕微鏡構造を明らかにした. 特定のスプライシング因子の放出とPrp43の結合を詳細に説明し,ILSの解体メカニズムを提案した.

キーワード:
DEAH-box ATPase/ヘリカースILS複合体Ntr コンプレックスNtr1 についてNtr2 についてPrp43 についてクリオ・エムイントロン・ラリアット・スプライソームmRNA前スプライシングスプライソームの解体

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