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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

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アミドを含む分子におけるアリファティックC-H結合の遠隔後期酸化

Takeshi Nanjo1, Emilio C de Lucca1, M Christina White1

  • 1Roger Adams Laboratory, Department of Chemistry, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|September 19, 2017
PubMed
まとめ

新しいイミダート塩の戦略により,薬剤にとって極めて重要なアミドの選択的C−H酸化が可能になる. この方法は,以前のN-保護技術の限界を克服し,薬剤発見の遅い段階の機能化の可能性を拡大します.

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