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Updated: Feb 22, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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バイオミメティック・トータル・シンセシス (±) -グリフィパビキサントン 経由 カチオン・サイクロアディション・サイクライゼーション・カスケード

Kyle D Reichl1, Michael J Smith1, Min K Song2

  • 1Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University , 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.

Journal of the American Chemical Society
|September 26, 2017
PubMed
まとめ

研究者は自然産物グリフィパビキサントンを簡潔に合成した. この生体模倣アプローチは,新しいダイエルス-アルダー反応を使用して,単一の前体分子から二次構造を作成しました.

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