腸内微生物群に関連した結腸癌の分子基礎:合成的視点

Alan R Healy1,2, Seth B Herzon1,3

  • 1Department of Chemistry, Yale University , New Haven, Connecticut 06520, United States.

PubMed
まとめ

研究者らは大腸がんに関連した コリバクチンのような 細菌代謝物を調べました 合成と生物合成の研究は,コリバクチンが遺伝子毒性イミンであることを明らかにし,DNAを損傷するメカニズムを確認した.

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