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Updated: Feb 22, 2026

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli
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The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli

Published on: January 13, 2013

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ロンゲラシンフィリンAの総合成

Jian Li1, Wenhao Zhang1, Fei Zhang1

  • 1State Key Laboratory of Bioorganic and Natural Products Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.

Journal of the American Chemical Society
|September 29, 2017
PubMed
まとめ

複雑な天然産物であるロングラシンフィリンAの最初の非対称的全合成が達成されました. 重要なステップには,銀触媒によるサイクル化,ラジカルサイクル化,および六環構造の構築のためのサイクル添加が含まれています.

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