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Updated: Jun 15, 2026

Nuclei Isolation from Mouse Cardiac Progenitor Cells for Epigenome and Gene Expression Profiling at Single-Cell Resolution
10:03

Nuclei Isolation from Mouse Cardiac Progenitor Cells for Epigenome and Gene Expression Profiling at Single-Cell Resolution

Published on: May 12, 2023

発血性 心臓 の 空間 的 遺伝子 プロフィール: 繊維 細胞 が SOX を 装着 する

Hadi Khalil1, Marjorie Maillet1, Jeffery D Molkentin2

  • 1From Department of Pediatrics, University of Cincinnati (H.K., M.M., J.D.M.), and Howard Hughes Medical Institute (J.D.M.), Cincinnati Children's Hospital Medical Center, OH.

Circulation
|October 11, 2017
PubMed
まとめ

No abstract available in PubMed .

キーワード:
エディトリアルフィブロブラスト心不全mRNAプロファイリング転写因子

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Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues

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Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...