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Updated: Feb 21, 2026

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
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人間のTRPML1チャネル構造は,開いた形状と閉じた形状にある.

Philip Schmiege1,2, Michael Fine3, Günter Blobel1

  • 1Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10065, USA.

Nature
|October 12, 2017
PubMed
まとめ

研究者らは,閉じた状態と開いた状態のトランシーント受容体潜在性ムコリピン1 (TRPML1) チャンネルの構造を明らかにした. これは,カルシウムシグナル伝達,リソソーム機能,およびIV型粘脂症についての洞察を提供します.

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