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米国における成人の尿中のナトリウムとカリウムと血圧の関連性:全国保健栄養調査,2014年
Sandra L Jackson1,2, Mary E Cogswell2, Lixia Zhao2,3
1Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA (S.L.J.) SLJackson@cdc.gov.
Circulation
|October 13, 2017
まとめ
高いナトリウムと低いカリウム摂取量は,米国の成人の血圧に大きな影響を及ぼします. この研究では24時間の尿排泄でナトリウムとカリウムを測定した.
科学分野:
- 心血管の健康
- 栄養学的流行病学
- 公衆衛生
背景:
- 食中のナトリウムとカリウムの摂取は,血圧の調節と関連しています.
- 以前の研究は,自己報告された摂取量とリコールバイアスのために制限に直面しました.
- 24時間の尿排泄は,電解質の摂取量をより正確に測定できます.
研究 の 目的:
- 24時間の尿中のナトリウムとカリウムの排泄と血圧の間の関連性を評価する.
- これらの電解質の排泄と米国の成人における高血圧の流行の関係を評価する.
主な方法:
- 2014年国立健康栄養調査 (NHANES) の横断データを使用した.
- 20歳から69歳の米国人766人を含め,全血圧と24時間尿量検査を行った.
- 通常の電解質分泌量の見積もりで,日々の変動を調整する.
主要な成果:
- ナトリウム分泌量の増加は,シストリック血圧とダイアストリック血圧の上昇と相関する.
- カリウムの分泌量の増加は,シストリック血圧の低下と相関する.
- ナトリウムとカリウムの比率が高くなり,シストリック血圧が上昇した.
- 高血圧のリスクは,ナトリウム分泌量が高くなり,カリウム分泌量が高くなり,減少した.
結論:
- 尿中のナトリウム分泌と血圧の間の有意な用量反応関係が確認された.
- 尿中のカリウム排出と血圧の逆相関が示された.
- 発見は,米国成人の心血管健康のためのナトリウムとカリウムバランスの重要性を強調しています.
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