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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

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カップリング N-H デプロトン化,C-H アクティベーション,および酸化:無金属C ((sp3) -H アミネーションと無保護アニライン

Christopher J Evoniuk1, Gabriel Dos Passos Gomes1, Sean P Hill1

  • 1Florida State University , Tallahassee, Florida 32306, United States.

Journal of the American Chemical Society
|October 18, 2017
PubMed
まとめ

この研究では,保護されていないアニリンと分子酸素によるt-BuOKを用いた分子内酸化C-Hアミネーションの軽い方法が導入されています. このプロセスは,シネジスティックなベース,ラジカル,酸化作用によって,移行金属のないN-ヘテロサイクルを効率的に合成します.

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