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Updated: Feb 20, 2026

Author Spotlight: Investigating the Mechanisms and Inducing Models of Polycystic Ovary Syndrome
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Author Spotlight: Investigating the Mechanisms and Inducing Models of Polycystic Ovary Syndrome

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多囊性卵巣症候群における不妊症に対する治療-回答

Xiao-Ke Wu1, Elisabet Stener-Victorin2, Heping Zhang3

  • 1Department of Obstetrics and Gynecology, Heilongjiang University of Chinese Medicine, Harbin, China.

JAMA
|October 20, 2017
PubMed
まとめ

No abstract available in PubMed .

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Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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