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Updated: Feb 20, 2026

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
09:09

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Published on: September 20, 2016

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D4ドーパミン受容体の高解像度構造は,選択的アゴニストの発見を可能にします

Sheng Wang1, Daniel Wacker1, Anat Levit2

  • 1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7365, USA. shengunc@email.unc.edu dwacker@email.unc.edu bshoichet@gmail.com bryan_roth@med.unc.edu.

Science (New York, N.Y.)
|October 21, 2017
PubMed
まとめ

D4ドーパミン受容体の高解像度結晶構造は,抗精神病薬の結合とシグナル伝達に関する洞察を示しています. この突破は神経精神疾患に対する 新しい選択的ドーパミン受容体アゴニストの発見を可能にします

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