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Updated: Feb 20, 2026

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
08:58

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Published on: March 11, 2017

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FOXO1アクティベーター/抑制剤の選択的抑制は,肝臓のグルコース処理を調節する

Fanny Langlet1, Rebecca A Haeusler2, Daniel Lindén3

  • 1Naomi Berrie Diabetes Center, Columbia University, New York, NY 10032, USA; Department of Medicine, Columbia University, New York, NY 10032, USA.

Cell
|October 24, 2017
PubMed
まとめ

研究者らは,SIN3Aをインスリン抵抗性の重要な要因として特定し,脂肪の蓄積を引き起こすことなく,選択的にグルコースの生産をターゲットにすることで,糖尿病を治療する新たな方法を明らかにしました.

キーワード:
糖尿病薬物療法肝臓のグルコース生成ヘパトステアトシスインスリン抵抗性インスリン敏感剤脂質生成選択モジュール小分子阻害剤トランスクリプション・リプレッサ

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