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Updated: Feb 20, 2026

Nanoscale Characterization of Liquid-Solid Interfaces by Coupling Cryo-Focused Ion Beam Milling with Scanning Electron Microscopy and Spectroscopy
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感受性の高いバッテリー材料とインターフェースの原子構造が,冷凍電子顕微鏡で明らかになった

Yuzhang Li1, Yanbin Li1, Allen Pei1

  • 1Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|October 28, 2017
PubMed
まとめ

低温電子顕微鏡はバッテリー材料を保存し,リチウム金属デンドライトの成長方向と固体電解質インターフェーズナノ構造を改善します.

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Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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Preparation of Samples for Electron Microscopy

To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
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