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NCOA1/STAT6 タンパク質相互作用の標的抑制

Yeongju Lee1, Heeseok Yoon2, Sung-Min Hwang3

  • 1Department of Chemistry and Division of Advanced Material Science, Pohang University of Science and Technology (POSTECH) , Pohang 37673, South Korea.

Journal of the American Chemical Society
|November 2, 2017
PubMed
まとめ

新しいステープルペプチドは,NCOA1/ STAT6複合体を破壊し,STAT6媒介による転写を阻害する. このペプチドは,タンパク質とタンパク質の相互作用をターゲットにするための化学的探査機と潜在的な治療的リードとして機能します.

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