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Updated: Feb 19, 2026

Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique
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コヘシン除去によって明らかになったクロマチンの2つの独立した組織形態

Wibke Schwarzer1, Nezar Abdennur2, Anton Goloborodko3

  • 1Developmental Biology Unit. European Molecular Biology Laboratory. 69117 Heidelberg, Germany.

Nature
|November 3, 2017
PubMed
まとめ

Nipblを削除すると染色体の折りたたみが再編成され,トポロジカルアソシエイトドメイン (TAD) が消滅するが,ゲノムコンパートメントは保存される. これは,クロマチンの状態に関連したより細かい区画構造を明らかにします.

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