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Updated: Feb 19, 2026

Polysome Profiling without Gradient Makers or Fractionation Systems
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リボソモパシー 集団の強さ

Eric W Mills1, Rachel Green2

  • 1Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Science (New York, N.Y.)
|November 4, 2017
PubMed
まとめ

リボソームの欠陥によって引き起こされるリボソーム病は,特定の細胞および組織の問題につながります. リボソームホメオスタシスは,なぜこれらの障害が他の組織よりも特定の組織に影響を及ぼし,タンパク質発現に影響を与えるのかを説明します.

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The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
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