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Updated: Feb 19, 2026

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

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ミトコンドリア内膜AAA+プロテアゼYME1の構造は,基板処理の洞察を与える

Cristina Puchades1,2, Anthony J Rampello3, Mia Shin1,2

  • 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute HZ 175, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|November 4, 2017
PubMed
まとめ

ミトコンドリア内部のAAA+プロテアゼであるYME1の原子構造を明らかにしました この構造は,ATPASEが質管理のためのスパイラル階段メカニズムを通して展開されたタンパク質基板をどのように関与させ,転位させるかを示しています.

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