MerR重金属受容体は,トポロジ的に新しい転写複合体のポジティブな活性化を媒介する

T V O'Halloran1, B Frantz, M K Shin

  • 1Department of Chemistry, Northwestern University, Evanston, Illinois 60208.

Cell
|January 13, 1989
PubMed
まとめ

重金属のストレスは,MerRタンパク質を通じて細菌の遺伝子発現を誘発し,それは水銀イオン耐性オペレオンを直接活性化します. このタンパク質-DNAの相互作用は,転写制御のためのRNAポリメラーゼとのユニークな空間的配置を含んでいます.

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