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Updated: Feb 19, 2026

Reconstitution of Msp1 Extraction Activity with Fully Purified Components
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細胞タンパク質VMS1はリボソーム品質管理とミトコンドリアおよび細胞ホメオスタシスを関連付けている

Toshiaki Izawa1, Sae-Hun Park2, Liang Zhao2

  • 1Department of Cellular Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany; Division of Cell Biology, Biomedical Center, Faculty of Medicine, University of Munich, Großhaderner Strasse 9, 82152 Martinsried, Germany.

Cell
|November 7, 2017
PubMed
まとめ

酵母細胞はミトコンドリアの 欠陥のあるタンパク質を作り出し 変換の過程で停止します タンパク質Vms1とリガゼLtn1は,これらの異常タンパク質を品質管理に誘導し,細胞の生存能力を維持することによって,毒性を防止します.

キーワード:
キャット・テイルLtn1 についてRqc2 についてVms1 についてミトコンドリアミトコンドリア毒性タンパク質の集積タンパク質の輸入リボソーム品質管理リボソームの停滞

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