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Updated: Feb 19, 2026

Single-Molecule Imaging of Nuclear Transport
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Published on: June 9, 2010

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核孔を通過する輸送を規制することによって,YAPの核侵入を誘発する

Alberto Elosegui-Artola1, Ion Andreu2, Amy E M Beedle3

  • 1Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), 08028 Barcelona, Spain.

Cell
|November 7, 2017
PubMed
まとめ

核に及ぼす力により,核孔のメカニズムが変化することで,YAP (Yes-associated protein) の核インポートが直接増加する. この機械感知メカニズムは 癌や再生のようなプロセスにおける 転写制御に影響を与えます

キーワード:
海馬の経路原子力顕微鏡メカノセンシングメカニカルトランスデュークション分子機械的安定性核力学核の毛穴原子力輸送剛性センサー転写規制について

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