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Updated: Feb 13, 2026

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses
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Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses

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MHC-I ゲノタイプは腫瘍性変異のパターンを制限する

Rachel Marty1, Saghar Kaabinejadian2, David Rossell3

  • 1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA.

Cell
|November 7, 2017
PubMed
まとめ

ヒト白血球抗原クラスI (MHC-I) のプレゼンテーションは癌の変異を形作る. 患者のMHC- Iゲノタイプは,腫瘍発症と癌の感受性に影響を与える腫瘍変異の発生を予測します.

キーワード:
抗原の表示癌について癌に罹患する傾向がんに対する感受性の予測ヒト白血球抗原免疫編集免疫学について免疫療法メジャー・ヒストコンパティビリティ・コンプレックスネオアンチゲン

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