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Updated: Jul 25, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
11:44

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

規制性転写因子,IRF-1による内生IFN-αおよびIFN-β遺伝子の誘導

T Fujita1, Y Kimura, M Miyamoto

  • 1Institute for Molecular and Cellular Biology, Osaka University, Japan.

Nature
|January 19, 1989
PubMed
まとめ

インターフェロン調節因子-1 (IRF-1) は,インターフェロンアルファおよびベータ遺伝子を直接誘導することができます. この研究では,IRF-1遺伝子の発現だけで,ウイルストリガーなしで哺乳類細胞の静かなインターフェロン遺伝子を活性化することが示されています.

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Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization08:57

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