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Updated: Feb 19, 2026

Inducing a Site Specific Replication Blockage in E. coli Using a Fluorescent Repressor Operator System
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Inducing a Site Specific Replication Blockage in E. coli Using a Fluorescent Repressor Operator System

Published on: August 21, 2016

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レドックスに敏感なレプリソーム構造の変化はゲノムの完全性を保ちます

Kumar Somyajit1, Rajat Gupta2, Hana Sedlackova1

  • 1Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.

Science (New York, N.Y.)
|November 11, 2017
PubMed
まとめ

ペロキシレドキシン2 (PRDX2) によって検知される活性酸素種 (ROS) を増加させる. この感知メカニズムは複製フォークを遅らせ,複製のストレスを軽減し,がん細胞の適応を助けます.

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