小麦Dゲノムの祖先であるAegilops tauschiiのゲノム配列
Ming-Cheng Luo1, Yong Q Gu2, Daniela Puiu3
1Department of Plant Sciences, University of California, Davis, California, USA.
Nature
|November 17, 2017
まとめ
Aegilops tauschiiは,小麦Dゲノムの祖先であり,現在,参照品質のゲノム配列を持っています. この研究で明らかになったのは その高度な繰り返しの性質が 急速なゲノム進化と 遺伝子の複製を促すということです
科学分野:
- ゲノミクス
- 植物生物学
- 進化生物学
背景:
- エギロップス・タウシイ (Aegilops tauschii) は,六倍体小麦 (Triticum aestivum) のDゲノムの二倍体祖先である.
- その巨大で反復的なゲノムは 以前の参照品質の配列決定を妨げました
- エイ タウシイは小麦の改良に不可欠な遺伝資源です
研究 の 目的:
- Aegilops tauschii ssp の参照品質のゲノム配列を生成する. ストロングラタ アデション AL8/78
- Aeのゲノム構造と進化の動態を調査する. タウシィ
- ゲノム進化における 繰り返し配列の役割を理解する
主な方法:
- オーダーされたクローンゲノムシーケンシング
- 全ゲノムショットガンシーケンシング
- バイオナノ光学ゲノムマッピング
主要な成果:
- 高品質のリファレンスゲノム配列をAEに タウシィ AL8/78 が成功しました.
- エーだ タウシイのゲノムは 前例のない 類似性の高い 繰り返し配列を示しています
- 他の植物ゲノムと比べると Ae タウシイは より分散した複製遺伝子と より速い染色体の進化を示しています
- 再結合率は他の草のゲノムとの共線性喪失と相関する.
結論:
- 同じような重複するシーケンスが 大量に存在します タウシイが再結合の誤りを起こす可能性が高い.
- これらの誤差は遺伝子複製と 急速な構造的染色体変化に寄与し ゲノム進化を速める.
- この発見は 草のゲノムを形作る進化的メカニズムと 小麦の遺伝的改善の 潜在的ターゲットについての洞察を提供します
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