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Updated: Feb 18, 2026

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
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PD-1はT細胞リンパ生成を抑制するハプロイン素です

Tim Wartewig1,2, Zsuzsanna Kurgyis1,2, Selina Keppler1,2

  • 1Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany.

Nature
|November 17, 2017
PubMed
まとめ

プログラムされた死-1 (PD-1) は,腫瘍性T細胞受容体シグナル伝達に抵抗することで,T細胞リンパ腫の腫瘍抑制剤として作用する. 人間のT細胞リンパ腫における頻繁なPD-1変異は,がん治療におけるその臨床的重要性を強調する.

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