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Updated: Feb 18, 2026

Automated Separation of C. elegans Variably Colonized by a Bacterial Pathogen
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Automated Separation of C. elegans Variably Colonized by a Bacterial Pathogen

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NAIP5によるフラゲリン検出の構造的基礎:病原体の免疫回避を制限する戦略

Jeannette L Tenthorey1, Nicole Haloupek1, José Ramón López-Blanco2

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|November 18, 2017
PubMed
まとめ

この研究は,バクテリアのフラゲリンによってフラゲリン-NAIP5-NLRC4炎症体がどのように活性化されるかを明らかにしています. この構造的洞察は,リガンドによるヌクレオチド結合ドメインレウシン豊富なリピート (NLR) タンパク質の活性化により,宿主防衛機構を理解するための基礎を提供します.

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