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Updated: Feb 18, 2026

Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor
09:21

Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor

Published on: January 4, 2016

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NRF1は,コレステロール・ホメオスタシスの中心となるER膜センサーです

Scott B Widenmaier1, Nicole A Snyder1, Truc B Nguyen1

  • 1Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard TH Chan School of Public Health, Boston, MA 02115, USA.

Cell
|November 18, 2017
PubMed
まとめ

核エリソイド因子2関連因子-1 (Nrf1) は,エンドプラズマの網膜内の過剰なコレステロールを感知し,管理する. Nrf1欠乏症は肝臓の損傷を引き起こし,コレステロールの恒常性における重要な役割を強調しています.

キーワード:
Nfe2L1 についてNrf1 についてコレステロールエンドプラズマの網膜免疫代謝炎症肝臓メタボリズムストレス

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