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Updated: Feb 18, 2026

Stepwise Dosing Protocol for Increased Throughput in Label-Free Impedance-Based GPCR Assays
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Stepwise Dosing Protocol for Increased Throughput in Label-Free Impedance-Based GPCR Assays

Published on: February 21, 2020

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生理学的な利益のためのバイアスGPCRシグナリングのチューニング

Skylar Spangler1, Michael R Bruchas2

  • 1Department of Anesthesiology, Division of Basic Research, Washington University School of Medicine, St. Louis, MO 63110, USA.

Cell
|November 18, 2017
PubMed
まとめ

研究者はより安全なオピエット鎮痛剤を 設計する新しい方法を開発しました このアプローチは,動物モデルにおけるGタンパク質結合受容体 (GPCR) 信号バイアスを,痛み緩和と危険な呼吸抑制の間の用量分離と相関させる.

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