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Updated: Feb 18, 2026

In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation
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Published on: April 30, 2014

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ニューロデゲネレーションにおける非伝統的な翻訳の再考

Fen-Biao Gao1, Joel D Richter2, Don W Cleveland3

  • 1Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Cell
|November 18, 2017
PubMed
まとめ

反復関連非AUG (RAN) 翻訳を含む非従来の翻訳は,神経変性疾患に寄与する. これらのメカニズムを研究することで 翻訳生物学と病理学の両方への洞察が得られます

キーワード:
ALS についてC9ORF72 についてディペプチドリピートタンパク質フロントテンポラル認知症近親性のスタートコドン拡張を繰り返す翻訳アップストリーム オープン リーディング フレーム

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