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Updated: Feb 18, 2026

Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins
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Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins

Published on: May 22, 2017

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チャネルロドプシン2によるイオン伝導に関する構造的洞察

Oleksandr Volkov1, Kirill Kovalev1,2,3,4, Vitaly Polovinkin1,2,3,5

  • 1Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

Science (New York, N.Y.)
|November 25, 2017
PubMed
まとめ

高解像度構造は,チャネルロドプシン2 (ChR2) の開閉を明らかにします. 重要なシフ基と関連するゲートはイオンフローを制御し,光遺伝的ツール規制の洞察を提供します.

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