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Updated: Feb 18, 2026

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
08:53

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092

Published on: October 2, 2017

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ペニシリン結合タンパク質の機能的にユニークなファミリーの特定

Michael A Welsh1, Atsushi Taguchi1, Kaitlin Schaefer1,2

  • 1Department of Microbiology and Immunobiology, Harvard Medical School , Boston, Massachusetts 02115, United States.

Journal of the American Chemical Society
|November 29, 2017
PubMed
まとめ

研究 者 たち は,バクテリア の 細胞 壁 に d-アミノ 酸 を 組み込む ユニークな 低分子量 ペニシリン 結合 タンパク質 (PBPs) を 発見 し まし た. これらの新しいPBPは,細菌の細胞壁の組立と抗生物質の標的に関する新しい生化学的研究を可能にします.

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Protein Families02:47

Protein Families

Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key...
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Drug binding to proteins is a complex phenomenon influenced by various drug-related factors, each playing a significant role in the interaction between drugs and proteins within the body.
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Structure of Porins

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