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次世代接続マップ:L1000プラットフォームと最初の1,000,000のプロファイル

Aravind Subramanian1, Rajiv Narayan1, Steven M Corsello2

  • 1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Cell
|December 2, 2017
PubMed
まとめ

コネクティビティ・マップ (CMap) は,L1000プロフィールメソッドを使用して1,000倍に拡大されました. この拡張されたCMapは,薬の発見と臨床応用のための遺伝子発現シグネチャーを介して,遺伝子,薬物,疾患を結びつけています.

キーワード:
機能的ゲノミクス化学生物学遺伝子発現プロファイリング

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