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Updated: Feb 17, 2026

Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins
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Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins

Published on: December 12, 2013

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トリメチアミンN酸化物は,タンパク質と尿素の好ましい相互作用を阻害することによって,尿素の変性化に対抗する

Pritam Ganguly1, Pablo Boserman2, Nico F A van der Vegt3

  • 1Department of Chemistry and Biochemistry, University of California at Santa Barbara , Santa Barbara, California 93106, United States.

Journal of the American Chemical Society
|December 8, 2017
PubMed
まとめ

トリメチアミンN酸化物 (TMAO) は,分子相互作用を最適化することによって,尿素のタンパク質変性効果を逆行します. この保護メカニズムはペプチドの組成に依存し,細胞のオスモライト機能に関する新しい洞察を提供します.

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