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ジカワクチンの開発における伝統と革新

Ernesto T A Marques1, Donald S Burke2

  • 1Graduate School of Public Health, and the Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA; Instituto Aggeu Magalhães, Department of Virology and Experimental Therapeutics, FIOCRUZ-Pernambuco, Brazil.

Lancet (London, England)
|December 9, 2017
PubMed
まとめ

No abstract available in PubMed .

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Vaccine Production01:23

Vaccine Production

144
Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
144
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