孤立した左束分岐ブロックにおける機能的異常. 腸間非同期性の効果について
C L Grines1, T M Bashore, H Boudoulas
1Department of Internal Medicine, Ohio State University, Columbus.
Circulation
|April 1, 1989
まとめ
LBBB (Left Bundle Branch Block) は,左心室の機能に重大な遅延を引き起こし,腹動時間と心音の振幅に影響を及ぼします. これにより,LBBB患者のセプトの貢献度が低下し,エジェクション分子が全体的に低下します.
科学分野:
- 心臓病学 心臓病学
- 心臓電気生理学 心臓電気生理学
- 心血管画像検査 (CVDI) について
背景:
- 左束のブランクブロック (LBBB) は,心室活性化シーケンスに影響する心伝導異常である.
- LBBBが心室力学と血液動力学に及ぼす機能的影響を理解することは,患者の管理に不可欠です.
研究 の 目的:
- 孤立左束分岐ブロック (LBBB) が,左心室と右心室の機能とタイミングに与える影響を調査する.
- LBBB患者の心臓のメカニカルイベントを,正常な被験者と比較する.
主な方法:
- アペックスカルディオグラフィー,フォノカルディオグラフィー,エレクトロカルディオグラフィー,エコーカルディオグラフィー (2DとデュアルMモード) および放射性核体心房図 (RNV) を含むマルチモダルアプローチを使用しました.
- 孤立したLBBBを持つ18人の患者と10人の正常な対照群を比較した.
主要な成果:
- LBBBは,左心室のシストリックおよびダイアストリックイベントの有意な遅延を示し,ダイアストルを短縮し,右心室と左心室のダイアストリック時間比率を増加させた.
- LBBBでは最初の心臓音 (S1) の振幅 (S1/S2比) の減少が観察され,これは弁寄附体の分離が拡大したためであった.
- LBBBにおける異常な心室間隔膜の動きは,非同期的な心室収縮と放出を反映した.
- RNVは,対照群と比較して,LBBB患者のセプト地域エジェクション分子が低下し,グローバルエジェクション分子が低下したことを示した.
結論:
- 隔離されたLBBBは正常な心室間同期を妨害し,左心室機能の障害につながります.
- この研究は,LBBB.におけるダイアストリックタイミング,心臓音の特徴,および地域/グローバル放出分数の有意な変化を強調しています.
- これらの発見は,LBBBが全体的な心臓機能に及ぼす機械的な影響を強調しています.
さらに関連する動画
関連する概念動画
01:28Mechanism of Cardiac Arrhythmias
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
01:29Disturbances in Heart Rhythm
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
01:22Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
01:29Dysrhythmias III: Characteristics of Dysrhythmias
Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per minute.
01:18Dysrhythmias IV: Characteristics of Bradyarrhythmias
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
01:25ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...