バイオインスピレーションによる異質イオンポンプ膜:非対称的なイオン群分布から生じる一方的な選択的ポンプと制御可能なゲート特性
Zhen Zhang1,2, Pei Li3, Xiang-Yu Kong4
1Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, P. R. China.
Journal of the American Chemical Society
|December 21, 2017
まとめ
選択的で片方向の流れと 制御可能なゲーティングを備えた 賢明な人工イオンポンプを開発しました バイオインスピレーションを受けたこの膜は,エネルギー,水処理,バイオセンシングのアプリケーションのためのナノ流体装置を進歩させています.
科学分野:
- 材料科学
- ナノテクノロジー
- バイオミメティック工学
背景:
- 人工イオンポンプは 生物学的ポンプを模倣して エネルギー変換,バイオセンシング,脱塩に不可欠です
- 現在のバイオインスピレーションポンプは 選択性,方向性,制御可能なゲーティングがなく 機能性が制限されています
- "スマート"イオン輸送を達成するには,高い選択性,方向性,制御可能なゲーティングが必要です.
研究 の 目的:
- 選択性と方向性を強化したバイオインスピレーションによる異質イオンポンプ膜を開発する.
- 人工イオンポンプシステムで制御可能なイオンゲート機能を達成する.
- 生物学的システムにインスパイアされた 先進的なナノ流体装置のためのプラットフォームを作成します
主な方法:
- バイオインスピレーションによる異質イオンポンプ膜の製造
- ブロックコポリマー膜の犠牲コーティングとプラズマ移植技術を使用します.
- イオン輸送を制御するために非対称的なイオン群分布を導入します.
主要な成果:
- 発達した膜は片方向の選択的イオンポンプを示している.
- 制御可能なイオンゲート性能を示しています.
- 非対称なイオン群分布は,新しい輸送行動の重要な要因として特定されています.
結論:
- 異質イオンポンプは,スマートイオン輸送プロセスをシミュレートするためのプラットフォームを提供します.
- この技術は,エネルギー変換,水処理,バイオセンシングにおける人工ナノ流体装置の応用を促進します.
- この研究は,高度な,バイオミテックイオン輸送システムへの重要な一歩を表しています.
関連する概念動画
Potentiometry: Membrane Electrodes
1.8K
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
1.8K
Ion Exchange
1.3K
Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
1.3K
ATP Driven Pumps I: An Overview
10.0K
ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
10.0K
Pore Transport and Ion-Pair Transport
1.4K
Pore transport and ion-pair formation are critical mechanisms for the absorption and distribution of drugs in the body.
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct...
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct...
1.4K
Non-gated Ion Channels
8.3K
Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism....
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism....
8.3K
Ion Channels
91.6K
The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
91.6K


