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Updated: Feb 16, 2026

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Dicerは,dsRNA末端を認識するために異なるモジュールを使用します

Niladri K Sinha, Janet Iwasa, Peter S Shen

  • 1Department of Biochemistry, University of Utah, Salt Lake City, UT 84112, USA. bbass@biochem.utah.edu peter.shen@biochem.utah.edu.

Science (New York, N.Y.)
|December 23, 2017
PubMed
まとめ

ドロソフィラDicer-2は,そのヘリケースドメインを使用して,これまで知られていなかった抗ウイルス防御のメカニズムである鈍い二重鎖RNA (dsRNA) 末端を結合します. この解き放つとスレッドするプロセスは,効果的な免疫のためにdsRNAの分裂を最適化します.

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